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Abstract
Grant Number: 5R24CA095841-02 Project Title: Cancer Center Microarray Bioinformatics Facility
PI Information: Name Title ARGRAVES, W. SCOTT. argraves@musc.edu ASSOCIATE PROFESSOR Abstract: DESCRIPTION (provided by applicant): The overall goal of this proposal is to establish a DNA Microarray and Bioinformatics Resource Facility at the Hollings Cancer Center (HCC), Medical University of South Carolina. The planned NCI-funded resource facility will build upon recent institutional investments and create a comprehensive infrastructure comprised of faculty, support staff, state-of-the-art instrumentation and advanced computational/statistical analysis resources required to facilitate the use of DNA microarray analysis to identify profiles of genes expressed in specific cancer-related processes. Major goals of the proposal include providing investigators with expert consultation and assistance through all critical phases of the process of DNA microarray analysis including the initial experimental planning phase, molecular biology phase and through to the data analysis phase. The latter will involve implementation of both commercial software applications as well as a number of advanced computer algorithms developed by bioinformatics specialists supported through the core. Finally, the resource facility will create an internet-accessible database of gene expression profile information collected by HCC investigators to make this data available to the scientific community at large.
Public Health Relevance:
This Public Health Relevance is not available.Thesaurus Terms:
biomedical facility, cancer information system, informatics, microarray technology, molecular biology information system
Institution: MEDICAL UNIVERSITY OF SOUTH CAROLINA 19 Hagood Ave., Suite 606 CHARLESTON, SC 29425 Fiscal Year: 2003 Department: REGENERATIVE MEDICINE AND CELL BIOLOGY Project Start: 01-APR-2002 Project End: 31-MAR-2007 ICD: NATIONAL CANCER INSTITUTE IRG: ZCA1