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Scope Note:

research method that uses small molecules to change the way proteins work directly in real time rather than indirectly by manipulating their genes; used to identify which proteins regulate different biological processes, to understand in molecular detail how proteins perform their biological functions, and to identify small molecules that may be of medical value; the term chemical genetics indicates that the approach uses chemistry to generate the small molecules and that it is based on principles that are similar to classical genetic screens.

Term Number:

5004-0012