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okadaic acid
See for:
OKA
Broader Terms:
animal extract
Broader Terms:
ether
Broader Terms:
marine toxin
Broader Terms:
phosphatase inhibitor
Broader Terms:
tumor promoter
Scope Note:
a cyclic polyether ionophore extracted from the black sponge Halichondria; inhibits protein phosphatases such as Cdc25 which serve as off switches for cell proliferation, and therefore acts as a tumor promoter; NLM also lists as a vasoconstrictor.
Term Number:
4001-0096
Send your comments to: Melody Lowe