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mixed lymphocyte reaction test

See for:

MLC test

See for:

MLR test

Broader Terms:

histocompatibility typing

Scope Note:

measure of histocompatibility at the HLA locus: peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days; lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not; in the one-way MLC test, the lymphocytes from one of the individuals are inactivated thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.

Term Number:

2935-6010


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