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loss of heterozygosity
See for:
LOH
Broader Terms:
gene mutation
Broader Terms:
neoplasm /cancer diagnosis
Related Terms:
neoplastic process
Scope Note:
genetic phenomenon due to deletion or mutation in one allele of a polymorphic gene, as detected by expression after cell fusion; used as a test for tumor-promoting mutations; do not confuse with "loss of heterogeneity" which applies to diverse cell populations within a tissue.
Term Number:
4003-0032
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