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Scope Note:

family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway; participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation; have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.

Term Number:

1129-2735