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folate antagonist

Used for:

piritrexim

Used for:

tetrahydrofolate antagonist

Broader Terms:

antimetabolite

Broader Terms:

vitamin antagonist

Narrower Terms:

aminopterin

Narrower Terms:

methotrexate

Scope Note:

inhibitors of the enzyme, dihydrofolate reductase, which converts dihydrofolate to tetrahydrofolate; frequently used in cancer chemotherapy.

Term Number:

1174-5583


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